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Literature Detail
Nature Communications2017
Massively parallel digital transcriptional profiling of single cells
这篇文献会作为平台方法、软件或流程的证据来源,用于帮助理解方法背景和应用边界。
Authors
作者信息
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Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary W. Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler
Abstract
摘要
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This paper describes a high-throughput droplet-based single-cell RNA-seq system that enabled large-scale digital transcriptional profiling. It is a key experimental foundation for 10x Genomics workflows and motivates the preprocessing steps performed by tools such as Cell Ranger.