clusterProfiler: an R package for comparing biological themes among gene clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han, Qing-Yu He

This paper presents clusterProfiler, an R package that implements methods for analyzing and visualizing functional profiles of gene clusters. The package supports over-representation analysis and gene set enrichment analysis of Gene Ontology and KEGG pathways, providing statistical analysis and rich visualization for interpreting functional enrichment results from high-throughput experiments.